I've had both the M-Audio boxes (um, 410 or 4 something...two mic inputs and two plugs for four simultaneous) and currently have a Presonus box (Firepod, 8 in). In my experience both have been very good boxes and I could recommend either one no problem.
However, can't say why but if I was looking for another 2-mic input box, I'd probably go with Presonus again. I like 'em.
Dee
"When life's a biatch, be a horny dog"
Amps: Marshall JVM 410H w/ Plexi Cap mod, Choke Mod & Negative Feedback Removal mod, 4x12", Behringer GMX110, Amplitube 3/StealthPedal
Half a dozen custom built/bastardized guitars all with EMG's, mostly 85's, Ibanez Artwood acoustic & Yamaha SGR bass, Epiphone Prophecy SG, Vox Wah, Pitchblack tuner plus assorted pedals, rack gear etc. for home studio use.