I've got the older unit, and have played the newer one and the Line 6. I prefer the older Vox to the newer one, but that may just be familiarity. Both sound pretty great to me, and I'm looking for lots of tone and timbre versatility that you can get easily with the amp and speaker models. I do think it sounds more tube-y than other effects units I've used.
As for the Line 6, I swore off them after getting one, having huge problems with switches not working right, and general flimsiness. Eventually replaced that with another, and still had problems. Took it back and walked away. The Vox is a tank by comparison, and I need the toughness when I'm using for gigging.
helliott in Hamilton
Guitars -- 2 PRS CE 24s 85/15 pups, PRS semi-hollow CE 22, Fender Baja Telecaster; Gibson Les Paul Standard; 80s Strat updated with custom 69 pups, Anniversary Strat with Fat 50s, Epiphone Sheraton re-issue; Yamaha 5-string bass; Yamaha TBS 6 and 12 string acoustics,Takamine acoustic, Fender nylon string acoustic
Amps -- Mesa Boogie Lone Star; Boss Katana 100, Peavey Blueamaster 2x10, Line 6 Helix
Pedals etc: Mosfet Full Drive 2; Ibanez Tube Screamer; Fairfield Barbershop OD, Diamond Compressor; Voodo Sparkledrive, Boss Digital Delay DD7; Boss TU2 Chromatic Tuner; Cry Baby wah