I'm very pleased with my quiver of tones, be it guitar > cable > Egnater Tweaker,
or guitar > HD500 > Tweaker. The HD500 is a GAS killer.
I've D/L'ed HD500 user's patches and adjusted them to my ear, so there is little else I want or need.

That said, I'd like to get a Fender Mustang to be my second amp to split dual signal to, and a Tele for variety.