I am by no means a guitarist worth mentioning, but the more I think about it, the more I like the "less is more" philosophy. I don't have a ton of pedals, but the only ones that are always in my chain are my tuner (does that count?), DVM OD2, and my Digitech delay and reverb pedals. I have a few others, but they mainly gather dust.

On the reverse side of things Premier Guitar had a big write up on a few pedal switching systems, some costing well over a grand. After reading that, I can see why so many pros have gone to Axe-FX or something similar if they use a ton of effects.