I've run the AC Tone in my pedal chain and also directly into the effects loop return of my HRD. With the latter, it was hard to keep the volume down to a reasonable level, but it sounded quite good. Keep in mind I play at home in a relatively small room, so it doesn't take much for the output to get uncomfortably loud. Haven't tried it through a DI box rather than an amp yet, but may try that at my church some time.

I really like how the pedal sounds with the drive around 11 - 12 o'clock and the voice around 3 o'clock, run through my BYOC Tweed Royal set to a low/clean output level. Just a really juicy, rich tone, even at very reasonable volumes.