Rev, I got my M-Audio FireWire 410 FULLY functional under Windows 10 and can get crazy low recording latency. Here's a familiar tune I just recorded this afternoon.

Guitar: Gibson Les Paul Goldtop
Amp: Scuffham Amps S-Gear 2.7
DAW: Tracktion 7
Plugins: Mackie Final Mix / Focusrite EQ and Comp

https://soundcloud.com/pete-92/like-a-hurrincane

Cheers!