If it's just the standard, thin poly finish that's on most MM necks, you can easily sand it off. I've done that on three MM necks and then had no problems shooting lacquer afterwards. It's easy to tell when you've got all the poly off. The sanding residue starts out a milky white color and then turns to plain maple sanding dust. It doesn't take very long to do. Then you simply shoot the bare wood with a lacquer sanding sealer and then the lacquer (or vintage amger tint dye, then clear lacquer).
The other alternative is to cover the poly with clear shellac as a base coat for the lacquer. You can't shoot lacquer right onto poly, but shellac being an organic compound is pretty much a universal undercoat. But, the whole reason for using nitro lacquer is so that you can get a nice thin but hard finish that buffs out to a brilliant gloss. So why spray it over poly and shellac first?
Ah, nothing relieves the discomfort of GAS pains like the sound of the UPS truck rumbling down your street. It's like the musician's Beano.