Absolutely!
I'm loaded for bear over here with nut files from .009 through whatever the largest Stewart Macdonald has, and then they move on to Swiss needle files to cover bass strings.

There's a box filled with nut blanks of mostly unbleached bone (for the bone) and a few bleached in 1/4" for Fenders and larger stuff for Gibsons, acoustics and other goodies, and there are also some Tusq and older graphite ones as well as chunks of Corian saved from a few sink cutouts.

I really think pearl looks classy, is extremely hard, but it is very expensive and a bit rough on the tools.

In a pinch I have cut off a piece of string, placed it in the slot, put the string back and yanked the scrap backwards into place for tuning and intonation.

It will stay there for quite some time if it's an unwound, and you are careful not to knock it out during a string change, and it's slippy slidey for vibrato work so tuning is solid this way.