Quote Originally Posted by duhvoodooman
Define "good lead tone". What sound are you going for?

In general, I find that the sequence of:
  1. switching to Manual mode with the effects on Bypass,
  2. selecting one of the 11 amp models and dialing in the volume & tone stack, and
  3. turning off Bypass, selecting and fine-tuning the effect I want to use

works best for me. My favorite amp models with my Strat are the Boutique Clean, Black 2x12, Tweed 4x10 and AC30TB. For the first two, if I want some break-up, I use an overdrive pedal like the Bad Monkey. For the latter two, just push the Gain knob past 12 noon....
What I'm looking for is a good lead tone with some nice overdrive/moderate distortion. I haven't found that sweet spot on the amp yet with some of the tones. Love the Bassman but I'd like a little more gain. I haven't tried pedals yet, so that might give me what I need.

I'm still getting used to this amp too (had it for 2 weeks) so it may just be a matter of experimentation.

Do you use your neck pup or bridge for solos? Just curious.